October 9, 2023

The pre-analytical phase is a fundamental stage in the success of a diagnostic result. And when it comes to cervical cancer screening, it’s no different.

The Kolplast CellPreserv System has made liquid cytology viable for all laboratories, whether private or public

The pre-analytical phase is a fundamental stage in the success of a diagnostic result. And when it comes to cervical cancer screening, it’s no different. Cervical cancer ranks third among the most frequent tumors in the Brazilian female population, according to the National Cancer Institute (INCA). In most cases, it is associated with persistent infection by certain oncogenic types of Human Papillomavirus (HPV). The strategy for reducing incidence and mortality is early diagnosis and screening (WHO, 2007a).

In this sense, liquid-based cytology is a solution for reducing recurrent failures in sample collection. The liquid-based technique reduces cell loss and, through automated processing, provides a slide with better cell arrangement and free of non-diagnostic artifacts, making it easier to read and increasing sensitivity in detecting intraepithelial lesions. In addition, liquid collection also allows other tests to be carried out on the same sample.

Kolplast CellPreserv System

Brazil already has a national method, the Kolplast CellPreserv System, which has made liquid cytology viable for all laboratories, whether private or public. Manaus City Hall, for example, has invested in the CellPreserv diagnostic method in an effort to combat the high rate of cervical cancer, making liquid-based cytology available in all Basic Health Units. “Amazonas leads the ranking of cervical cancer cases and in order to tackle the disease we understood that it was necessary to invest in diagnostic methods. That’s why we sought out liquid-based cytology, which is a more effective and modern system. The method offers greater sensitivity and specificity, giving us a 95% certainty of early diagnosis. In this way, we speed up the process for early treatment of our women, with extremely high chances of a cure,” said Shádia Fraxe, Manaus’ municipal health secretary.

Manufactured to international standards, the Kolplast CellPreserv System presents a set of solutions for the collection, transportation and automated processing of gynecological (and non-gynecological) samples. The inclusion of the Kolplast CellPreserv method in routine cervical cancer screening fulfills the function of preserving cell morphology for up to six weeks at room temperature with excellence. And from the same sample it is also possible to carry out molecular tests such as: Oncoproteins E6 and E7; Chlamydia; Neisseria Gonorrhoeae; Mycoplasma Genitalium; Mycoplasma Homínis; Candida; Ureaplasma Parvum; Trichomonas Vaginalis; Herpes 1 and 2; Thrombophilic Profile, HPV, among others.